Trial Protocol Desk

Paste a clinical study synopsis and get the sample size worked out free in your browser - two-sample t-test or two-proportion z-test, superiority or non-inferiority, any allocation ratio, inflated for dropout, with sensitivity at 90% power and at a 10% smaller effect - plus the power your planned enrolment really buys; the synopsis checked for a primary endpoint whose timepoint is a scheduled visit, multiplicity, a comparator, randomisation and blinding, a non-inferiority margin, measurable criteria, safety monitoring and a data monitoring committee, an analysis plan and promotional claims; and the Schedule of Activities drawn. A metered run critiques the design topic by topic or drafts the eight core protocol sections, and every sample-size number in the reply must be one of the page's. A drafting aid for investigators, sponsors and CROs. Built on the SkillSafe skill @anthropics/clinical-trial-protocol-skill.